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VAR2CSA and protective immunity against pregnancy-associated<i>Plasmodium falciparum</i>malaria

25 Oct 2007

Abstract excerpt

People living in areas with stable transmission of P. falciparum parasites acquire protective immunity to malaria over a number of years and following multiple disease episodes. Immunity acquired this way is mediated by IgG with specificity for parasite-encoded, clonally variant surface antigens (VSA) on the surface of infected erythrocytes (IEs). However, women in endemic areas become susceptible to P....

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PMID: 17958922
DOI: 10.1017/s0031182007000121

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