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Article

A umuDC-independent SOS pathway for frameshift mutagenesis.

Molecular & general genetics : MGG - 1 Nov 1992

Maenhaut-Michel G, Janel-Bintz R, Fuchs R P

Abstract excerpt

The chemical carcinogen N-acetoxy-N-2-acetylaminofluorene induces mainly frameshift mutations, which occur within two types of sequences (mutation hot spots): -1 frameshift mutations within contiguous guanine sequences and -2 frameshift mutations within alternating GC sequences such as the NarI and BssHII restriction site sequences. We have investigated the genetic control of mutagenesis at these sequences by...

Topics

Acetoxyacetylaminofluorene
Bacterial Proteins
Base Sequence
DNA-Directed DNA Polymerase
Escherichia coli
Escherichia coli Proteins
Frameshift Mutation
Genes, Bacterial
Genotype
Mutagenesis
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rec A Recombinases

Restriction Mapping

SOS Response, Genetics

Serine Endopeptidases

Ultraviolet Rays

Source

Identifiers

PMID: 1465109
DOI: 10.1007/BF00279383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1465109-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A umuDC-independent SOS pathway for frameshift mutagenesis.PMID 1465109Read ↗

Roles of recA mutant allele (recA495) in frameshift mutagenesis.Semantic proximity Read ↗

Induction of -2 frameshift mutations within alternating GC sequences by carcinogens that bind to the C8 position of guanine residues: development of a specific mutation assay.Semantic proximity Read ↗

Position of a single acetylaminofluorene adduct within a mutational hot spot is critical for the related mutagenic event.Semantic proximity Read ↗

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