Article
A umuDC-independent SOS pathway for frameshift mutagenesis.
Molecular & general genetics : MGG - 1 Nov 1992
Maenhaut-Michel G, Janel-Bintz R, Fuchs R P
Abstract excerpt
The chemical carcinogen N-acetoxy-N-2-acetylaminofluorene induces mainly frameshift mutations, which occur within two types of sequences (mutation hot spots): -1 frameshift mutations within contiguous guanine sequences and -2 frameshift mutations within alternating GC sequences such as the NarI and BssHII restriction site sequences. We have investigated the genetic control of mutagenesis at these sequences by...
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