Article
SOS and UVM pathways have lesion-specific additive and competing effects on mutation fixation at replication-blocking DNA lesions.
Journal of bacteriology - 1 Mar 1999
Rahman M S, Humayun M Z
Abstract excerpt
Escherichia coli cells have multiple mutagenic pathways that are induced in response to environmental and physiological stimuli. Unlike the well-investigated classical SOS response, little is known about newly recognized pathways such as the UVM (UV modulation of mutagenesis) response. In this study, we compared the contributions of the SOS and UVM pathways on mutation fixation at two representative...
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