Article
Roles of recA mutant allele (recA495) in frameshift mutagenesis.
Biochimie - 1 Apr 1991
Janel-Bintz R, Maenhaut-Michel G, Takahashi M, Fuchs R P
Abstract excerpt
The chemical carcinogen N-acetoxy-N-2-acetylaminofluorene (N-AcO-AAF) induces frameshift mutations located within two types of specific sequences (mutation hot spots): i) contiguous guanine sequences and ii) alternating GC sequences. The genetic requirements of these frameshift events were invest...
Topics
- Alleles
- DNA Repair
- Escherichia coli
- Frameshift Mutation
- Genes, Bacterial
- Mutagenesis
- Rec A Recombinases
- Repetitive Sequences, Nucleic Acid