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Article

Exocrine cell transdifferentiation in dexamethasone-treated rat pancreas.

Virchows Archiv : an international journal of pathology - 1 Jan 2004

Lardon Jessy, Huyens Niki, Rooman Ilse, Bouwens Luc

Abstract excerpt

Injured pancreatic tissue, for example, after duct ligation, undergoes remodeling, which involves the replacement of exocrine acini by duct-like structures. This acinoductal metaplasia is probably at least partly due to transdifferentiation of amylase-positive, cytokeratin-20 (CK20)-negative acinar cells into amylase-negative, CK20-positive duct-like cells. Due to the kinetics of these phenotypic changes,...

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PMID: 14648221
DOI: 10.1007/s00428-003-0930-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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