Article
Differentiation of islet cells in long-term culture.
Pancreas - 1 May 2000
Schmied B M, Liu G, Matsuzaki H, Ulrich A, Hernberg S, Moyer M P, Weide L, Murphy L, Batra S K, Pour P M
Abstract excerpt
Our previous studies in the hamster pancreatic cancer model have shown that exocrine pancreatic cancer arises from ductal/ductular cells, as well as from within the islets, most probably from islet precursor (stem) cells. To identify and characterize these cells, we established a long-term culture from isolated hamster islets and investigated their growth, differentiation, and expression of biomarkers. Islets...
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