Article
Transdifferentiation molecular pathways of neonatal pig pancreatic duct cells into endocrine cell phenotypes.
Transplantation proceedings - 1 Nov 2004
Basta G, Racanicchi L, Mancuso F, Guido L, Luca G, Macchiarulo G, Brunetti P, Calafiore R
Abstract excerpt
Restrictions in availability of cadaveric human donor pancreata have intensified the search for alternate sources of pancreatic endocrine tissue. We have undertaken to assess whether nonendocrine pancreatic tissue, with special regard to ducts, including epithelial cells, and retrieved from neonatal pig pancreata that are used for islet isolation, may under special in vitro culture conditions generate endocrine...
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