Article
Differentiation of pancreatic acinar cells into duct-like cells in vitro.
Laboratory investigation; a journal of technical methods and pathology - 1 Nov 1993
Arias A E, Bendayan M
Abstract excerpt
BACKGROUND: Previous studies have shown that a combination of both the extracellular matrix and secretagogues plays critical roles in the maintenance of well-differentiated pancreatic acinar cells in culture. In the present study, we have shown that, upon proper stimulation, acinar cells change their growth pattern and morphologic appearance to a duct like phenotype. EXPERIMENTAL DESIGN: Both rat and guinea pig...
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