Article
Transdifferentiation of human islets to pancreatic ductal cells in collagen matrix culture.
Differentiation; research in biological diversity - 1 Oct 1996
Yuan S, Rosenberg L, Paraskevas S, Agapitos D, Duguid W P
Abstract excerpt
Transdifferentiation is a change from one differentiated phenotype to another, involving morphological and functional phenotypic markers. Stability of the cellular phenotype is probably related to the extracellular milieu, as well as cytoplasmic and nuclear components that interact to control gene expression, and the conversion of cell phenotype is likely to be accomplished by selective enhancement of gene...
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