Article
Genome-wide TDT analysis in a localized population with a high prevalence of multiple sclerosis indicates the importance of a region on chromosome 14q.
Genes and immunity - 1 Dec 2003
Giedraitis V, Modin H, Callander M, Landtblom A M, Fossdal R, Stefansson K, Hillert J, Gulcher J
Abstract excerpt
Epidemiological studies show that susceptibility to multiple sclerosis (MS) has a strong genetic component, but apart from the HLA gene complex, additional genetic factors have proven difficult to map in the general population. Thus, localized populations, where MS patients are assumed to be more closely related, may offer a better opportunity to identify shared chromosomal regions. We have performed a...
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