Article
Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes.
Human molecular genetics - 1 Jun 2013
Cortes Adrian, Field Judith, Glazov Evgeny A, Hadler Johanna, Stankovich Jim, Brown Matthew A
Abstract excerpt
Multiple sclerosis (MS) is a common chronic inflammatory disease of the central nervous system. Susceptibility to the disease is affected by both environmental and genetic factors. Genetic factors include haplotypes in the histocompatibility complex (MHC) and over 50 non-MHC loci reported by genome-wide association studies. Amongst these, we previously reported polymorphisms in chromosome 12q13-14 with a...
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