Article
Recent advances in genetic analysis of multiple sclerosis: genetic associations and therapeutic implications.
Expert review of neurotherapeutics - 1 Sept 2007
Niino Masaaki, Fukazawa Toshiyuki, Kikuchi Seiji, Sasaki Hidenao
Abstract excerpt
Epidemiological studies have confirmed that genetic factors are a key component in the pathogenesis of multiple sclerosis (MS) and that those determining MS susceptibility have been extensively studied. Many papers have been published regarding the heritable differences useful in genetic studies; these include variations in DNA, such as single-nucleotide polymorphisms, microsatellites and insertion/deletion...
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