A high-density screen for linkage in multiple sclerosis.

doi:10.1086/444547

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Article

A high-density screen for linkage in multiple sclerosis.

American journal of human genetics - 1 Sept 2005

Sawcer Stephen, Ban Maria, Maranian Mel, Yeo Tai Wai, Compston Alastair, Kirby Andrew, Daly Mark J, De Jager Philip L, Walsh Emily, Lander Eric S, Rioux John D, Hafler David A, Ivinson Adrian, Rimmler Jacqueline, Gregory Simon G, Schmidt Silke, Pericak-Vance Margaret A, Akesson Eva, Hillert Jan, Datta Pameli, Oturai Annette, Ryder Lars P, Harbo Hanne F, Spurkland Anne, Myhr Kjell-Morten, Laaksonen Mikko, Booth David, Heard Robert, Stewart Graeme, Lincoln Robin, Barcellos Lisa F, Hauser Stephen L, Oksenberg Jorge R, Kenealy Shannon J, Haines Jonathan L

Abstract excerpt

To provide a definitive linkage map for multiple sclerosis, we have genotyped the Illumina BeadArray linkage mapping panel (version 4) in a data set of 730 multiplex families of Northern European descent. After the application of stringent quality thresholds, data from 4,506 markers in 2,692 individuals were included in the analysis. Multipoint nonparametric linkage analysis revealed highly significant linkage in...

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Identifiers

PMID: 16080120
DOI: 10.1086/444547
PMCID: PMC1226210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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