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Article

Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms.

PloS one - 1 Jan 2008

Comabella Manuel, Craig David W, Camiña-Tato Montse, Morcillo Carlos, Lopez Cristina, Navarro Arcadi, Rio Jordi, Montalban Xavier, Martin Roland

Abstract excerpt

Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system with an important genetic component and strongest association driven by the HLA genes. We performed a pooling-based genome-wide association study of 500,000 SNPs in order to find new loci associated with the disease. After applying several criteria, 320 SNPs were selected from the microarrays and individually...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18941528
DOI: 10.1371/journal.pone.0003490
PMCID: PMC2566815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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