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Article

Betacellulin: a mitogen from pancreatic beta cell tumors

12 Mar 1993

Abstract excerpt

Betacellulin, a member of the epidermal growth factor family, has been identified in the conditioned medium of cell lines derived from mouse pancreatic beta cell tumors. Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. The carboxyl-terminal domain of betacellulin has 50 percent sequence similarity with that of rat transforming...

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PMID: 8456283
DOI: 10.1126/science.8456283

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