Article
Autocrine growth stimulation by secreted Kaposi fibroblast growth factor but not by endogenous basic fibroblast growth factor.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Feb 1990
Wellstein A, Lupu R, Zugmaier G, Flamm S L, Cheville A L, Delli Bovi P, Basilico C, Lippman M E, Kern F G
Abstract excerpt
We studied the different potentials of a secreted and a nonsecreted member of the fibroblast growth factor (FGF) family to induce autocrine growth stimulation in human adrenal cortex carcinoma cells (SW-13). These epithelial cells express basic FGF (bFGF) cell surface receptors, and picomolar con...
Topics
- Adenocarcinoma
- Adrenal Cortex Neoplasms
- Animals
- Down-Regulation
- Fibroblast Growth Factor 2
- Fibroblast Growth Factor 4
- Fibroblast Growth Factors
- Heparin
- Humans
- Mice
- Mice, Nude
- Neoplasm Proteins
- Neoplasm Transplantation