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Article

Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing.

Trends in immunology - 1 Dec 2003

Girardin Stephen E, Hugot Jean Pierre, Sansonetti Philippe J

Abstract excerpt

Nod2 (Card15) belongs to the family of the recently described Nod molecules, which also includes the closely related protein Nod1 (Card4). Nod proteins have been initially described as intracellular activators of the caspase and NF-kappaB signaling pathways. Recent progress has enabled research to demonstrate genetically that NOD2 (CARD15) is involved in the predisposition to Crohn's disease and Blau syndrome. In...

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Source

Identifiers

PMID: 14644139
DOI: 10.1016/j.it.2003.10.007

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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