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Article

NOD2 and Crohn's disease: loss or gain of function?

Immunity - 1 Jun 2005

Eckmann Lars, Karin Michael

Abstract excerpt

The human nucleotide binding and oligomerization domain (NOD)-containing protein family consists of some 25 members related to the Apaf-1/Ced-4 family of apoptosis regulators and certain plant disease-resistance genes (Inohara et al., 2004). One member, NOD2 (CARD15), has gained recent prominence through its association with increased susceptibility to several clinically important human inflammatory diseases,...

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Source

Identifiers

PMID: 15963781
DOI: 10.1016/j.immuni.2005.06.004

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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