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Article

Core promoter/pre-core mutations are associated with lamivudine-induced HBeAg loss in chronic hepatitis B with genotype C.

Journal of hepatology - 1 Dec 2003

Asahina Yasuhiro, Izumi Namiki, Uchihara Masakatsu, Noguchi Osamu, Nishimura Yuki, Inoue Kazunari, Ueda Ken, Tsuchiya Kaoru, Hamano Kosei, Itakura Jun, Miyake Shozo

Abstract excerpt

BACKGROUND/AIMS: To clarify the factors associated with the efficacy of lamivudine. METHODS: Variables including basic core promoter (BCP) and pre-core (PreC) mutations were evaluated in 60 chronic hepatitis B e antigen (HBeAg)-positive patients with genotype C. Thirty patients were treated with lamivudine and the remaining 30 patients were age- and sex-matched controls. RESULTS: Severe fibrosis was significantly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 14642627
DOI: 10.1016/s0168-8278(03)00467-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Core promoter/pre-core mutations are associated with lamivudine-induced HBeAg loss in chronic hepatitis B with genotype C.PMID 14642627Read ↗

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