Article
Mutations of pre-core and basal core promoter before and after hepatitis B e antigen seroconversion.
World journal of gastroenterology - 14 Jan 2015
Kamijo Nozomi, Matsumoto Akihiro, Umemura Takeji, Shibata Soichiro, Ichikawa Yuki, Kimura Takefumi, Komatsu Michiharu, Tanaka Eiji
Abstract excerpt
AIM: To investigate the role of pre-core and basal core promoter (BCP) mutations before and after hepatitis B e antigen (HBeAg) seroconversion. METHODS: The proportion of pre-core (G1896A) and basal core promoter (A1762T and G1764A) mutant viruses and serum levels of hepatitis B virus (HBV) DNA, hepatitis B surface antigen (HBsAg), and HB core-related antigen were analyzed in chronic hepatitis B patients before...
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