Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in the basic core promoter region of hepatitis B virus. Relationship with precore variants and HBV genotypes in a Spanish population of HBV carriers.

Journal of hepatology - 1 Mar 2004

Jardi Rosendo, Rodriguez Francisco, Buti Maria, Costa Xose, Valdes Auristela, Allende Helena, Schaper Melanie, Galimany Roman, Esteban Rafael, Guardia Jaime

Abstract excerpt

BACKGROUND/AIMS: To determine the prevalence and significance of hepatitis B virus (HBV) basic core promoter (BCP) mutations and to establish their relationship with precore (preC) mutations, HBV genotypes and HBV-DNA levels. METHODS: BCP and preC mutations and genotypes were determined by sequencing. RESULTS: Genomic analysis was performed in 129 (71%) of 182 patients. BCP mutations were detected in 83% of 18...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine Transaminase
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B e Antigens

Share to Hepatitis B virus

Share to Protein Structure, Tertiary

Share to Viral Core Proteins

Share to Virus Replication

Source

Identifiers

PMID: 15123367
DOI: 10.1016/j.jhep.2003.11.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in the basic core promoter region of hepatitis B virus. Relationship with precore variants and HBV genotypes in a Spanish population of HBV carriers.PMID 15123367Read ↗

Basal core promoter and precore mutations among hepatitis B virus circulating in Brazil and its association with severe forms of hepatic diseases.Semantic proximity Read ↗

Precore and core promoter mutations, hepatitis B virus DNA levels and progressive liver injury in chronic hepatitis B.Semantic proximity Read ↗

Correlation of hepatitis B virus (HBV) genotypes and mutations in basal core promoter/precore with clinical features of chronic HBV infection.Semantic proximity Read ↗

Review on hepatitis B virus precore/core promoter mutations and their correlation with genotypes and liver disease severitySemantic proximity Read ↗

Clinical significance of hepatitis B virus precore and core promoter variants in Korean patients with chronic hepatitis B.Semantic proximity Read ↗

Clinical Features of Chronic Hepatitis B in Treatment-naive Asian Patients With Positive HBeAg and Coexisting Precore and/or Basal Core Promoter Mutations.Semantic proximity Read ↗

Sequential accumulation of the basal core promoter and the precore mutations in the progression of hepatitis B virus-related chronic liver disease.Semantic proximity Read ↗

Characterization of the basal core promoter and precore regions in anti-HBe-positive inactive carriers of hepatitis B virus.Semantic proximity Read ↗

The loss of HBeAg without precore mutation results in lower HBV DNA levels and ALT levels in chronic hepatitis B virus infection.Semantic proximity Read ↗

Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis.Semantic proximity Read ↗

Frequency and clinical significance of core promoter and precore region mutations in Tunisian patients infected chronically with hepatitis B.Semantic proximity Read ↗

Precore and Basal Core Promoter Hepatitis B Virus (HBV) Variants Are Present From a Young Age and Differ Across HBV Genotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.