Article
Comparison of sequence changes of precore and core promoter regions in HBeAg-positive chronic hepatitis B patients with and without HBeAg clearance in lamivudine therapy.
Journal of hepatology - 1 Jan 2006
Chen Chien-Hung, Lee Chuan-Mo, Lu Sheng-Nan, Changchien Chi-Sin, Wang Jyh-Chwan, Wang Jing-Houng, Hung Chao-Hung, Hu Tsung-Hui
Abstract excerpt
BACKGROUND/AIMS: The aim of this study was to compare the serial sequence changes of precore and core promoter regions in hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) patients with and without HBeAg clearance in lamivudine treatment. METHODS: Precore and core promoter genes of the hepatitis B virus (HBV) were sequenced from five serial serum samples of 74 HBeAg-positive CHB patients received...
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