Article
The loss of HBeAg without precore mutation results in lower HBV DNA levels and ALT levels in chronic hepatitis B virus infection.
Journal of gastroenterology - 1 Jan 2009
Kawabe Naoto, Hashimoto Senju, Harata Masao, Nitta Yoshifumi, Murao Michihito, Nakano Takuji, Shimazaki Hiroaki, Arima Yuko, Komura Naruomi, Kobayashi Kyoko, Yoshioka Kentaro
Abstract excerpt
BACKGROUND: The aim of this study was to investigate the correlation between precore (PC)/basal core promoter (BCP) mutations and the viral loads or activity of hepatitis in patients with chronic hepatitis B virus (HBV) infection. METHODS: HBV genotypes, PC mutations, BCP mutations, HBV DNA levels, and serological markers of HBV were analyzed in all the patients with chronic HBV infection seen in Fujita Health...
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