Article
High rate of core promoter and precore mutations in patients with chronic hepatitis B.
Hepatology international - 1 Apr 2015
Baqai Sumbella F, Proudfoot James, Yi Debbie H, Mangahas Michael, Gish Robert G
Abstract excerpt
BACKGROUND: The prevalence of precore (PC) and core promoter (CP) mutations in patients with chronic hepatitis B virus (HBV) infection (CHB) and their impact on liver disease is incompletely defined in the United States. METHODS: A retrospective chart review using a cross-sectional approach of 1,186 CHB patients was conducted. RESULTS: Of 926 patients tested for HBV e antigen (HBeAg), 37% were HBeAg+. Of 194...
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