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Article

Precore and core promoter mutations, hepatitis B virus DNA levels and progressive liver injury in chronic hepatitis B.

Journal of hepatology - 1 Sept 2002

Yotsuyanagi Hiroshi, Hino Kunihiko, Tomita Eiichi, Toyoda Joji, Yasuda Kiyomi, Iino Shiro

Abstract excerpt

BACKGROUND/AIMS: To elucidate the viral factors responsible for progressive liver injury in chronic hepatitis B. METHODS: We analyzed 179 persistently infected patients (21 asymptomatic carriers, 126 with chronic hepatitis and 32 with cirrhosis) with genotype C hepatitis B virus (HBV). HBeAg/anti-HBe, levels of HBV DNA, mutations in the basic core promoter (BCP) region at nucleotides 1762/1764 and mutation in the...

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Share to DNA, Viral
Share to Genotype
Share to Hepatitis B, Chronic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B Core Antigens

Share to Hepatitis B virus

Share to Liver Cirrhosis

Share to Point Mutation

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 12175631
DOI: 10.1016/s0168-8278(02)00180-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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