Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Smoking-dependent association between paraoxonase 1 M/L55 genotype and coronary atherosclerosis in males: an autopsy study.

Atherosclerosis - 1 Nov 2003

Rontu Riikka, Karhunen Pekka J, Ilveskoski Erkki, Mikkelsson Jussi, Kajander Olli, Perola Markus, Penttilä Antti, Koivisto Anna-Maija, Lehtimäki Terho

Abstract excerpt

High-density lipoprotein-associated paraoxonase 1 (PON1) enzyme can retard the oxidation of lipids. The methionine for leucine substitution at position 55 (M/L55) of the PON1 protein is associated with lower (MM genotype) or higher (ML or LL genotype) expression of the gene affecting serum level of PON1. We studied the association of the PON1 M/L55 genotype with the extent of atherosclerosis in an autopsy series...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aorta, Abdominal
Share to Aorta, Thoracic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aryldialkylphosphatase

Share to Autopsy

Share to Coronary Artery Disease

Share to Coronary Vessels

Share to Finland

Share to Statistics as Topic

Source

Identifiers

PMID: 14642403
DOI: 10.1016/j.atherosclerosis.2003.07.002

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Smoking-dependent association between paraoxonase 1 M/L55 genotype and coronary atherosclerosis in males: an autopsy study.PMID 14642403Read ↗

Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study.Semantic proximity Read ↗

Paraoxonase producing PON1 gene M/L55 polymorphism is related to autopsy-verified artery-wall atherosclerosis.Semantic proximity Read ↗

Relationship between high-density lipoprotein paraoxonase gene M/L55 polymorphism and carotid atherosclerosis differs in smoking and nonsmoking men.Semantic proximity Read ↗

The association of paraoxonase 1 gene L55M polymorphism with the extent and severity of coronary artery disease in the Turkish population and its dependence on gender.Semantic proximity Read ↗

PON1 M/L55 mutation protects high-risk patients against coronary artery disease.Semantic proximity Read ↗

Paraoxonase genotype, LDL-oxidation and carotid atherosclerosis in male life-long smokers.Semantic proximity Read ↗

Myeloperoxidase gene variation as a determinant of atherosclerosis progression in the abdominal and thoracic aorta: an autopsy study.Semantic proximity Read ↗

Paraoxonase 1 (PON1) Q192R genotypes and their interaction with smoking strongly increase atherogenicity and the Framingham risk score.Semantic proximity Read ↗

A paraoxonase gene polymorphism, PON 1 (55), as an independent risk factor for increased carotid intima-media thickness in middle-aged women.Semantic proximity Read ↗

Genetic associations and serum paraoxonase levels with atherosclerosis in western Iranian patients.Semantic proximity Read ↗

Paraoxonase 1 gene polymorphisms contribute to coronary artery disease risk among north Indians.Semantic proximity Read ↗

The PON1 M55L gene polymorphism is associated with reduced HDL-associated PAF-AH activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.