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Article

Paraoxonase genotype, LDL-oxidation and carotid atherosclerosis in male life-long smokers.

Free radical research - 1 Jun 2004

Van Himbergen Thomas, Roest Mark, De Waart Frouwkje, De Graaf Jacqueline, Voorbij Hieronymus, Van Tits Lambertus, Stalenhoef Anton

Abstract excerpt

Paraoxonase (PON-1) is a high-density lipoprotein (HDL) associated enzyme that hydrolyzes lipid peroxides in vitro, which may therefore protect against the onset of atherosclerosis. Heavy smokers are more exposed to oxidative stress and hence at high-risk for oxidative modification of LDL. Our hypothesis is that the anti-oxidative properties of PON-1 inhibit LDL oxidation, especially in populations exposed to...

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Identifiers

PMID: 15346646
DOI: 10.1080/1071576042000206496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Paraoxonase genotype, LDL-oxidation and carotid atherosclerosis in male life-long smokers.PMID 15346646Read ↗

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