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Article

Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study.

Pharmacogenetics - 1 Aug 2004

Rontu Riikka, Lehtimäki Terho, Ilveskoski Erkki, Mikkelsson Jussi, Kajander Olli, Goebeler Sirkka, Perola Markus, Penttilä Antti, Karhunen Pekka J

Abstract excerpt

High-density lipoprotein (HDL) level is inversely correlated with coronary heart disease risk. Paraoxonase-1 (PON1) is an HDL-associated anti-atherogenic enzyme. The activity of PON1 is affected by the methionine for leucine substitution at position 55 (M55L) and increased during regular moderate...

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Source

Identifiers

PMID: 15284530
DOI: 10.1097/01.fpc.0000114746.08559.00

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15284530-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study.PMID 15284530Read ↗

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