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Article

A paraoxonase gene polymorphism, PON 1 (55), as an independent risk factor for increased carotid intima-media thickness in middle-aged women.

Atherosclerosis - 1 Mar 2003

Fortunato Giuliana, Rubba Paolo, Panico Salvatore, Trono Daniela, Tinto Nadia, Mazzaccara Cristina, De Michele Mario, Iannuzzi Arcangelo, Vitale Dino F, Salvatore Francesco, Sacchetti Lucia

Abstract excerpt

Paraoxonase (PON) gene polymorphisms have been proposed as genetic markers of risk for cardiovascular disease (CVD). Sporadic results suggest they are correlated with intima-media thickness (IMT), an indicator of preclinical atherosclerotic disease. We have investigated whether polymorphisms PON 1 (M/L) 55, (Q/R) 192, PON 2 (S/C) 311 are related to site-specific carotid plaques in 310 middle-aged women. Subjects...

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PMID: 12618279
DOI: 10.1016/s0021-9150(02)00423-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A paraoxonase gene polymorphism, PON 1 (55), as an independent risk factor for increased carotid intima-media thickness in middle-aged women.PMID 12618279Read ↗

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