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Article

Neurobehavioral characteristics of mice with modified intermediate filament genes.

Reviews in the neurosciences - 1 Jan 2003

Lalonde R, Strazielle C

Abstract excerpt

Intermediate proteins comprise cytoskeletal elements that preserve the shape and structure of neurons. These proteins have been proposed to be involved in the onset and progression of amyotrophic lateral sclerosis (ALS), mainly characterized by motoneuron atrophy and paresis. In support of this hypothesis are the findings that genetically modified mice for intermediate filaments successfully mimic certain...

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Identifiers

PMID: 14640321
DOI: 10.1515/revneuro.2003.14.4.369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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