Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functions of intermediate filaments in neuronal development and disease

29 Oct 2003

Abstract excerpt

Five major types of intermediate filament (IF) proteins are expressed in mature neurons: the three neurofilament proteins (NF-L, NF-M, and NF-H), alpha-internexin, and peripherin. While the differential expression of IF genes during embryonic development suggests potential functions of these proteins in axogenesis, none of the IF gene knockout experiments in mice caused gross developmental defects of the nervous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Hereditary Neurological Disorders
Share to Skin and Cellular Biology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14598376
DOI: 10.1002/neu.10270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functions of intermediate filaments in neuronal development and diseasePMID 14598376Read ↗

Late Onset Death of Motor Neurons in Mice Overexpressing Wild-Type PeripherinSemantic proximity Read ↗

Defective axonal transport of neurofilament proteins in neurons overexpressing peripherinSemantic proximity Read ↗

Formation of Intermediate Filament Protein Aggregates with Disparate Effects in Two Transgenic Mouse Models Lacking the Neurofilament Light SubunitSemantic proximity Read ↗

Novel neurofilament light ( <i>Nefl</i> ) E397K mouse models of Charcot-Marie-Tooth type 2E (CMT2E) present early and chronic axonal neuropathySemantic proximity Read ↗

Neurobehavioral characteristics of mice with modified intermediate filament genes.Semantic proximity Read ↗

Neurofilament homeostasis and motoneurone degenerationSemantic proximity Read ↗

Neurofilaments: Novel findings and future challengesSemantic proximity Read ↗

Neuronal intermediate filaments and ALS: A new look at an old questionSemantic proximity Read ↗

An intact intermediate filament network is required for collateral sprouting of small diameter nerve fibers.Semantic proximity Read ↗

A role for neurofilaments in the pathogenesis of amyotrophic lateral sclerosis.Semantic proximity Read ↗

The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disordersSemantic proximity Read ↗

Novel neurofilament light (Nefl) E397K mouse models of Charcot-Marie-tooth type 2E (CMT2E) present early and chronic axonal neuropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.