Article
Neuronal intermediate filaments and neurodegenerative disorders.
Brain research bulletin - 28 Oct 2009
Perrot Rodolphe, Eyer Joël
Abstract excerpt
Intermediate filaments represent the most abundant cytoskeletal element in mature neurons. Mutations and/or accumulations of neuronal intermediate filament proteins are frequently observed in several human neurodegenerative disorders. Although it is now admitted that disorganization of the neurofilament network may be directly involved in neurodegeneration, certain type of perikaryal intermediate filament...
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