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Article

Genotypes of Pneumocystis jiroveci isolates obtained in Harare, Zimbabwe, and London, United Kingdom.

Antimicrobial agents and chemotherapy - 1 Dec 2003

Miller Robert F, Lindley Austin R, Ambrose Helen E, Malin Adam S, Wakefield Ann E

Abstract excerpt

Isolates of Pneumocystis jiroveci from sulfa-exposed and nonexposed patients from London, United Kingdom, and Harare, Zimbabwe, were genotyped. At the dihydropteroate synthase (DHPS) locus, there was evidence of selection pressure from sulfa drug exposure, and reversal of DHPS genotype ratios occurred when selection pressure was absent or was removed.

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Identifiers

PMID: 14638515
DOI: 10.1128/AAC.47.12.3979-3981.2003
PMCID: PMC296206

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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