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Article

Sulfa use, dihydropteroate synthase mutations, and Pneumocystis jirovecii pneumonia.

Emerging infectious diseases - 1 Oct 2004

Stein Cheryl R, Poole Charles, Kazanjian Powel, Meshnick Steven R

Abstract excerpt

A systematic review was conducted to examine the associations in Pneumocystis jirovecii pneumonia (PCP) patients between dihydropteroate synthase (DHPS) mutations and sulfa or sulfone (sulfa) prophylaxis and between DHPS mutations and sulfa treatment outcome. Selection criteria included study populations composed entirely of PCP patients and mutation or treatment outcome results for all patients, regardless of...

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Source

Open in PubMed Open full text

Identifiers

PMID: 15504261
DOI: 10.3201/eid1010.040362
PMCID: PMC3323254

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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