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Article

Dihydropteroate synthase gene mutation rates in Pneumocystis jirovecii strains obtained from Iranian HIV-positive and non-HIV-positive patients.

Medical mycology - 1 May 2015

Sheikholeslami Maryam-Fatemeh, Sadraei Javid, Farnia Parisa, Forozandeh Moghadam Mehdi, Emadikochak Hamid

Abstract excerpt

The dihydropteroate sulfate (DHPS) gene is associated with resistance to sulfa/sulfone drugs in Pneumocystis jirovecii. We investigated the DHPS mutation rate in three groups of Iranian HIV-positive and HIV-negative patients by polymerase chain reaction-restricted fragment length polymorphism analysis. Furthermore, an association between P. jirovecii DHPS mutations and strain typing was investigated based on...

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Source

Identifiers

PMID: 25631478
DOI: 10.1093/mmy/myu095

Genes

DHPS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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