Article
Pneumocystis jirovecii dihydropteroate synthase genotypes in French patients with pneumocystosis: a 1998-2001 prospective study.
Medical mycology - 1 Dec 2003
Latouche S, Lacube P, Maury E, Bolognini J, Develoux M, Girard P M, Godet C, Lebrette M G, Mayaud C, Guillot J, Roux P
Abstract excerpt
Dihydropteroate synthase gene (DHPS) mutations at codons 55 and 57 have been associated with sulfa/sulfone resistance in Pneumocystis jirovecii strains from patients who previously received prophylaxis. To evaluate the prevalence of these mutations, a portion of P. jirovecii DHPS gene was analyse...
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