Article
Genetic polymorphisms of CYP2C9 and CYP2C19 in the Beninese and Belgian populations.
British journal of clinical pharmacology - 1 Dec 2003
Allabi Aurel C, Gala Jean-Luc, Desager Jean-Pierre, Heusterspreute Michel, Horsmans Yves
Abstract excerpt
AIMS: To investigate the distribution of cytochrome P450 2C9 (CYP2C9) and 2C19 (CYP2C19) genotype frequencies in the Beninese and Belgian Caucasian populations. METHODS: Beninese (n = 111) and Belgian (n = 121) were genotyped for CYP2C9*2, *3, *4, *5, and *11 as well as for CYP2C19*2 and*3. RESULTS: The distribution of alleles was: CYP2C9*1: 95.5 vs. 82.2% (P < 0.001); CYP2C9*2: 0 vs. 10% (P < 0.001); CYP2C9*3: 0...
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