Article
Prevalence of the CYP2C19*2 (681 G>A), *3 (636 G>A) and *17 (‑806 C>T) alleles among an Iranian population of different ethnicities.
Molecular medicine reports - 1 Mar 2018
Dehbozorgi Mahshid, Kamalidehghan Behnam, Hosseini Iman, Dehghanfard Zahra, Sangtarash Mohammad Hossein, Firoozi Maryam, Ahmadipour Fatemeh, Meng Goh Yong, Houshmand Massoud
Abstract excerpt
Polymorphisms in the cytochrome P (CYP) 450 family may cause adverse drug responses in individuals. Cytochrome P450 2C19 (CYP2C19) is a member of the CYP family, where the presence of the 681 G>A, 636 G>A and 806 C>T polymorphisms result in the CYP2C19*2, CYP2C19*3 and CYP2C19*17 alleles, respectively. In the current study, the frequency of the CYP2C19*2, CYP2C19*3 and CYP2C19*17 alleles in an Iranian population...
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