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Genetic polymorphisms of cytochrome P450 enzymes: CYP2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5 in the Croatian population.

Drug metabolism and personalized therapy - 1 Mar 2017

Ganoci Lana, Božina Tamara, Mirošević Skvrce Nikica, Lovrić Mila, Mas Petar, Božina Nada

Abstract excerpt

BACKGROUND: Data on the frequency of pharmacogenetic polymorphisms in the Croatian population are limited. We determined and analyzed frequencies for the most important CYP2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5 genetic variants in the Croatian population. METHODS: 2637 subjects were included. Genotyping was performed by real-time polymerase chain reaction (PCR) using TaqMan® DME or TaqMan® SNP Genotyping...

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PMID: 28272018
DOI: 10.1515/dmpt-2016-0024

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