Article
Molecular Dissection of Microsatellite Instable Colorectal Cancer
2 Mar 2013
Abstract excerpt
UNLABELLED: Colorectal cancer was one of the first solid tumors to be classified on the basis of molecular profiling. Microsatellite instability has allowed researchers to distinguish a specific subtype of colorectal cancer that has a clearly identified molecular origin (mismatch repair deficiency), arises on a hereditary and sporadic basis, is linked to a clear clinicopathologic profile, and has prognostic...
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