Article
Colorectal carcinogenesis: from chromosomal evolution pathways to molecular pathogenesis.
Cancer genetics and cytogenetics - 1 Jan 1997
Remvikos Y, Muleris M, Salmon R J, Dutrillaux B
Abstract excerpt
Since the mid-1980s, research in the field of colorectal carcinogenesis has seen a series of breakthroughs such, as the process of loss of heterozygosity for large chromosomal segments and the consequent characterization of a series of suppressor genes considered to be the targets of the allelic deletions. More recently, a new perspective has been opened, with the discovery of germinal mutations of genes involved...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.