Article
Assessment of cumulated genetic alterations in colorectal cancer.
Histology and histopathology - 1 Oct 2003
Risques R A, Ribas M, Peinado M A
Abstract excerpt
Widespread genetic alterations are a common feature of most colorectal cancers. While specific recurrent alterations may reveal the involvement of a gene or set of genes in the biology of the disease, the cumulated genomic damage is likely to reflect the biological history of the neoplastic cells. Furthermore, the functional implications behind many of these genetic changes may show the evolutionary potential of...
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