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Article

Pygopus residues required for its binding to Legless are critical for transcription and development.

The Journal of biological chemistry - 13 Feb 2004

Townsley Fiona M, Thompson Barry, Bienz Mariann

Abstract excerpt

Pygopus and Legless/Bcl-9 are recently discovered core components of the Wnt signaling pathway that are required for the transcriptional activity of Armadillo/beta-catenin and T cell factors. It has been proposed that they are part of a tri-partite adaptor chain (Armadillo>Legless>Pygopus) that recruits transcriptional co-activator complexes to DNA-bound T cell factor. Here, we identify four conserved residues at...

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Identifiers

PMID: 14612447
DOI: 10.1074/jbc.M309722200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Pygopus residues required for its binding to Legless are critical for transcription and development.PMID 14612447Read ↗

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