Article
Wingless Signaling: A Genetic Journey from Morphogenesis to Metastasis.
Genetics - 1 Apr 2018
Bejsovec Amy
Abstract excerpt
This FlyBook chapter summarizes the history and the current state of our understanding of the Wingless signaling pathway. Wingless, the fly homolog of the mammalian Wnt oncoproteins, plays a central role in pattern generation during development. Much of what we know about the pathway was learned from genetic and molecular experiments in Drosophila melanogaster, and the core pathway works the same way in...
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