Article
Role of Ets/Id proteins for telomerase regulation in human cancer cells.
Experimental and molecular pathology - 1 Dec 2003
Xiao Xiaodong, Athanasiou Meropi, Sidorov Igor A, Horikawa Izumi, Cremona Gina, Blair Donald, Barret J Carl, Dimitrov Dimiter S
Abstract excerpt
Most human cancers express telomerase but its activity is highly variable and regulated by complex mechanisms. Recently, we have proposed that Ets proteins may be important for regulation of telomerase activity in leukemic cells. Here we provide further evidence for the role of Ets family members and related Id proteins in telomerase regulation and characterize the underlying molecular mechanisms. By using...
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