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Article

Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells.

Molecular and cellular biology - 1 Sept 2005

Takakura Masahiro, Kyo Satoru, Inoue Masaki, Wright Woodring E, Shay Jerry W

Abstract excerpt

The transcriptional regulation of the human telomerase catalytic subunit (hTERT) plays a critical role in telomerase activity. Approximately 200 bp of the proximal core promoter is responsible for basic hTERT expression; however, the function of the distal regulatory elements remains unclear. The transcription factor activator protein 1 (AP-1) is involved in cellular proliferation, differentiation,...

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Source

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Identifiers

PMID: 16135795
DOI: 10.1128/MCB.25.18.8037-8043.2005
PMCID: PMC1234330

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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