Article
Vascular endothelial growth factor gene polymorphisms and intracranial aneurysms.
Acta neurochirurgica - 1 Aug 2013
Fontanella Marco, Gallone Salvatore, Panciani Pier Paolo, Garbossa Diego, Stefini Roberto, Latronico Nicola, Rubino Elisa, Marengo Nicola, Ducati Alessandro, Pinessi Lorenzo, Rainero Innocenzo
Abstract excerpt
BACKGROUND: The exact pathophysiology of the development and rupture of saccular aneurysms is still controversial. Several lines of evidence indicate a role for inflammatory processes. Similarly, abnormal angiogenesis might be related to aneurysm growth. Expression of angiogenesis factors is higher in patients harboring aneurysms. The aim of this study was to verify the association of two functionally active...
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