Article
Functional polymorphism in the matrix metalloproteinase-9 promoter as a potential risk factor for intracranial aneurysm.
Stroke - 1 Dec 1999
Peters D G, Kassam A, St Jean P L, Yonas H, Ferrell R E
Abstract excerpt
BACKGROUND AND PURPOSE: There is convincing evidence that susceptibility to intracranial aneurysms (ICAs) has a genetic component. However, few studies have sought to identify functional variation in specific candidate genes that may predispose individuals to develop an ICA. METHODS: ICA cases and controls were genotyped for a simple length polymorphism in the promoter of matrix metalloproteinase-9 (MMP-9) to...
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