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Article

Carcinogen-induced impairment of enzymes for replicative fidelity of DNA and the initiation of tumours.

Carcinogenesis - 1 Mar 2004

Bignold Leon P

Abstract excerpt

Not all carcinogens are mutagens, and many mutagens are not carcinogens. Among related chemicals, small changes of structure can markedly influence carcinogenic potency. Many tumours are genetically unstable, but some, especially 'benign' types, rarely exhibit 'progression' or show other evidence of genetic instability. Cells of particular tumour types exhibit identifiable particular 'sets' of phenotypic...

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PMID: 14604890
DOI: 10.1093/carcin/bgh013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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