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Article

DNA repair: counteragent in mutagenesis and carcinogenesis-- accomplice in cancer therapy resistance.

Mutation research - 1 Apr 2000

Rajewsky M F, Engelbergs J, Thomale J, Schweer T

Abstract excerpt

DNA-reactive carcinogens and anticancer drugs induce many structurally distinct mutagenic and cytotoxic DNA lesions. The varying capability of normal and malignant cells to recognize and repair specific DNA lesions influences both cancer risk and the relative sensitivity or resistance of cancer cells towards cytotoxic agents. Using monoclonal antibody-based immunoanalytical assays, very low amounts of defined...

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PMID: 10767621
DOI: 10.1016/s1383-5742(00)00020-x

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AGT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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